Enteroviruses associated with the hemolytic-uremic syndrome.
Enteroviruses associated with the hemolytic-uremic syndrome.
复制标题
与溶血性尿毒症综合征相关的肠道病毒。
作者：
C. Ray;V. Tucker;David Harris;F. Cuppage;T. Chin
对 9 例溶血尿毒症综合征和 1 例暴发性紫癜进行了临床和病毒学研究。所有这些都被认为代表了不同程度的血管内凝血的例子。
病毒学研究表明肠道病毒，特别是柯萨奇病毒的感染频率很高。 10 名受试者中有 7 名发现了此类感染的证据，并且在其中 5 名受试者的家庭接触者中发现了类似的病毒感染。
对不同受试者和现有家庭接触者的研究表明，在所研究的 10 名受试者中，有 9 名患者和/或直系亲属近期患有肠道病毒感染。
有人认为，肠道病毒可能在引发这些疾病发病机制所涉及的一系列事件中发挥着作用。
Nine cases of the hemolytic-uremic syndrome and one case of purpura fulminans were studied clinically and virologically. All were thought to represent examples of varying degrees of intravascular coagulation.
Virological studies demonstrated a high frequency of infections with enteroviruses, particularly Coxsackie viruses. Evidence of such infections was found in 7 of the 10 subjects, and similar viral Infections were found among family contacts of 5 of the subjects.
Studies of the various subjects and the available family contacts demonstrated evidence of having recent enteroviral infection in the patient and/or the immediate family in 9 of the 10 subjects studied.
It is suggested that enteroviruses may have a role in initiating the sequence of events involved in the pathogenesis of these illnesses.