Tree Nut Allergy, Egg Allergy, and Asthma in Children
Tree Nut Allergy, Egg Allergy, and Asthma in Children
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DOI：
10.1177/0009922810384720
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发表时间：
2011-02-01
影响因子：
1.6
通讯作者：
Phipatanakul, Wanda
中科院分区：
文献类型：
--
作者：
Gaffin, Jonathan M.;Sheehan, William J.;Phipatanakul, Wanda
背景。食物过敏的儿童通常会并发哮喘。客观的。作者旨在确定食物过敏儿童中哮喘的患病率以及特定食物过敏与哮喘的关联。方法。针对 799 名食物过敏儿童，完成了有关食物过敏的家长问卷数据，并通过过敏致敏证实。多变量回归分析测试了食物过敏与报告的哮喘之间的关联。结果。在该队列中，哮喘患病率为 45.6%。在调整每种食物过敏、环境过敏和哮喘家族史后，鸡蛋过敏（比值比 [OR] = 2.0；95% 置信区间 [CI] = 1.3-3.2；P < .01）或树坚果过敏（OR = 2.0；95% CI = 1.1-3.6；P = .02）的儿童报告哮喘的几率明显更高。结论。对食物过敏的儿童人群中哮喘患病率很高。鸡蛋和坚果过敏与哮喘显着相关，与其他危险因素无关。
Background. Children with food allergies often have concurrent asthma. Objective. The authors aimed to determine the prevalence of asthma in children with food allergies and the association of specific food allergies with asthma. Methods. Parental questionnaire data regarding food allergy, corroborated by allergic sensitization were completed for a cohort of 799 children with food allergies. Multivariate regression analysis tested the association between food allergy and reported asthma. Results. In this cohort, the prevalence of asthma was 45.6%. After adjusting for each food allergy, environmental allergies, and family history of asthma, children with egg allergy (odds ratio [OR] = 2.0; 95% confidence interval [CI] = 1.3-3.2; P < .01) or tree nut allergy (OR = 2.0; 95% CI = 1.1-3.6; P = .02) had significantly greater odds of report of asthma. Conclusion. There is a high prevalence of asthma in the food-allergic pediatric population. Egg and tree nut allergy are significantly associated with asthma, independent of other risk factors.