Relation of cortical language distribution and cognitive function in surgical epilepsy patients
Relation of cortical language distribution and cognitive function in surgical epilepsy patients
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DOI：
10.1111/j.1528-1157.2000.tb00180.x
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发表时间：
2000-04-01
期刊：
影响因子：
5.6
通讯作者：
Doyle, W
中科院分区：
文献类型：
--
作者：
Devinsky, O;Perrine, K;Doyle, W
目的：研究语言位点的数量和空间分布与特定患者和癫痫相关变量之间的关系。非典型颞叶语言位点）与语言位点局限于颞叶后上和顶叶下外侧裂周区Wernicke区（WA）的患者进行比较。在一个连续的系列44左半球语言优势的复杂部分性癫痫发作患者左颞叶切除术前，皮质语言分布和认知function.Results的措施之间的相关性进行了比较：非典型颞叶语言网站的患者（组1）有显着减少年的教育，没有在WA（组2）的语言网站的患者。第1组患者的语言学习和流畅性比第2组患者差。IQ患者
Purpose: To investigate the relation between the number and spatial distribution of language sites and specific patient- and epilepsy-related variables.Methods: Patients with stimulation-induced reading or naming errors from anterior or inferior temporal cortex (i.e., atypical temporal language sites) were compared with those with language sites confined to Wernicke's area (WA) in the posterosuperior temporal and inferior parietal perisylvian area. In a consecutive series of 44 left hemisphere language dominant patients with complex partial seizures before left temporal lobectomy, correlations were compared between cortical language distribution and measures of cognitive function.Results: Patients with atypical temporal language sites (group 1) had significantly fewer years of education that did patients with language sites in WA (group 2). Patients in group 1 had poorer verbal learning and fluency than did patients in group 2. Patients with IQ