Human health risks of Pb and As exposure via consumption of home garden vegetables and incidental soil and dust ingestion: A probabilistic screening tool
Human health risks of Pb and As exposure via consumption of home garden vegetables and incidental soil and dust ingestion: A probabilistic screening tool
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DOI：
10.1016/j.scitotenv.2012.01.057
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发表时间：
2012-04-15
影响因子：
9.8
通讯作者：
Hale, Beverley
中科院分区：
文献类型：
--
作者：
Bacigalupo, Chris;Hale, Beverley
家庭种植的蔬菜的消费可能是一个显着的暴露途径砷（As）和铅（Pb）相对于直接偶然摄入的土壤，因此，估计这些风险的概率筛选工具开发使用回归模型相关的共同位于土壤和家庭花园（HG）蔬菜中的铅和砷的浓度建立从多个独立的研究和二维蒙特卡罗分析。对于大量食用HG蔬菜的消费者（即，一般人群中消费者的第95百分位数），汞的消费途径可以作为重要的偶然土壤和灰尘摄入无机砷，因此，应考虑在住宅环境中制定通用的健康为基础的土壤标准。预测铅危害商数（HQ）的估计在年幼的儿童中产生的HG消费量是4至10倍，低于直接偶然的土壤和灰尘摄入造成的暴露。用于表征幼儿（第95百分位数的202毫克/天）与终身住宅受体（第95百分位数的30毫克/天）的土壤/灰尘摄入率的差异是一个主要因素，有助于HQ和增量终身癌症风险（ILCR）之间观察到的相对差异导致这两个暴露途径铅铅和无机砷砷，分别。(C)2012爱思唯尔有限公司版权所有。
The consumption of home grown vegetables may represent a significant exposure pathway for arsenic (As) and lead (Pb) relative to direct incidental ingestion of soil, thus a probabilistic screening tool for estimating these exposures was developed using regression models relating co-located soil and home garden (HG) vegetable concentrations of Pb and As established from multiple independent studies and 2-dimensional Monte Carlo analyses. For high-quantity consumers of HG vegetables (i.e., the upper 95th percentile of consumers in the general population), the HG consumption pathway can be as significant as incidental soil and dust ingestion for inorganic As and, therefore, should be considered when developing generic health-based soil criteria in residential settings. Predicted Pb Hazard Quotient (HQ) estimates among young children resulting from HG consumption were 4- to 10-fold lower than exposures resulting from direct incidental soil and dust ingestion. The difference in soil/dust ingestion rates used to characterize young children (the 95th percentile of 202 mg/d) versus a lifetime residential receptor (the 95th percentile of 30 mg/d) was a primary factor contributing to the relative differences observed between HQ and incremental lifetime cancer risk (ILCR) resulting from these two exposure pathways for lead Pb and inorganic arsenic As, respectively. (C) 2012 Elsevier B.V. All rights reserved.