4-acetylaplykurodin B and aplykurodinone B, two ichthyotoxic degraded sterols from the Mediterranean mollusk Aplysia fasciata.
4-acetylaplykurodin B and aplykurodinone B, two ichthyotoxic degraded sterols from the Mediterranean mollusk Aplysia fasciata.
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DOI：
10.1021/np50085a027
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发表时间：
1992-07
影响因子：
5.1
通讯作者：
A. Spinella;M. Gavagnin;A. Crispino;G. Cimino;E. Martinez;J. Ortea;G. Sodano
中科院分区：
文献类型：
--
作者：
A. Spinella;M. Gavagnin;A. Crispino;G. Cimino;E. Martinez;J. Ortea;G. Sodano
本文报道了两种具有鱼毒活性的内酯化合物，即4-乙酰基黑色素B [1]和黑色素甲酮B [2]。通过光谱和化学方法确定了它们的结构，其与先前从黑田黑田黑田中分离的黑田黑丁B [3]密切相关。还研究了黑素衍生物中δ-和γ-内酯的相互转化。
Two ichthyotoxic lactones, 4-acetylaplykurodin B [1] and aplykurodinone B [2], were isolated from the external parts of the body of the mollusk Aplysia fasciata. Their structures, determined by spectroscopic and chemical means, are closely related to aplykurodin B [3] previously isolated from Aplysia kurodai. The interconversion of delta- and gamma-lactones in the aplykurodin derivatives has been also investigated.