Noncalcified Lung Nodules: Volumetric Assessment with Thoracic CT
Noncalcified Lung Nodules: Volumetric Assessment with Thoracic CT
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DOI：
10.1148/radiol.2511071897
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发表时间：
2009-04-01
期刊：
影响因子：
19.7
通讯作者：
Petrick, Nicholas
中科院分区：
文献类型：
--
作者：
Gavrielides, Marios A.;Kinnard, Lisa M.;Petrick, Nicholas
肺结节体积测量用于结节诊断，以及监测肿瘤对治疗的反应。体积测量的精确度和准确度取决于许多因素，包括图像获取和重建参数、结核特征以及结核分割和体积估计算法的性能。本文的目的是对已发表的有关肺结节的计算机断层扫描(CT)体积分析的研究进行综述。确定了一些在体积精度方面研究不足的领域，包括非固体结节的测量、螺距和截面重叠的影响以及呼吸运动的影响。讨论了对体模扫描以及临床数据的公共数据库的需求。审查指出，需要继续进行研究，以检查肺结节评估中涉及的众多相关变量对体积准确性的影响。了解和量化CT评估肺结节时体积测量误差的来源，将是制定方法的第一步，以便通过改进系统将误差降至最低，并正确解释任何剩余的误差。(C)RSNA，2009年
Lung nodule volumetry is used for nodule diagnosis, as well as for monitoring tumor response to therapy. Volume measurement precision and accuracy depend on a number of factors, including image-acquisition and reconstruction parameters, nodule characteristics, and the performance of algorithms for nodule segmentation and volume estimation. The purpose of this article is to provide a review of published studies relevant to the computed tomographic (CT) volumetric analysis of lung nodules. A number of underexamined areas of research regarding volumetric accuracy are identified, including the measurement of non-solid nodules, the effects of pitch and section overlap, and the effect of respiratory motion. The need for public databases of phantom scans, as well as of clinical data, is discussed. The review points to the need for continued research to examine volumetric accuracy as a function of a multitude of interrelated variables involved in the assessment of lung nodules. Understanding and quantifying the sources of volumetric measurement error in the assessment of lung nodules with CT would be a first step toward the development of methods to minimize that error through system improvements and to correctly account for any remaining error. (c) RSNA, 2009