Chronic pain in persons with myotonic dystrophy and facioscapulohumeral dystrophy
Chronic pain in persons with myotonic dystrophy and facioscapulohumeral dystrophy
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DOI：
10.1016/j.apmr.2007.08.153
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发表时间：
2008-02-01
影响因子：
4.3
通讯作者：
McDonald, Craig M.
中科院分区：
文献类型：
--
作者：
Jensen, Mark P.;Hoffman, Amy J.;McDonald, Craig M.
目的：确定强直性肌营养不良（MMD）和面肩肱型肌营养不良（FSHD）工作年龄成人疼痛的性质和范围。设计：回顾性横断面调查。设置：基于社区的调查。参与者：MMD和FSHD受试者的方便样本。干预措施：不适用。主要结果测量：疼痛的总体强度和持续时间。疼痛推断，疼痛部位，疼痛治疗和疼痛治疗提供的缓解。结果：更多的受试者与FSHD（82%）比MMD（64%）报告疼痛。两个诊断组最常报告的疼痛部位是下背部（66% MMD。74% FSHD）和腿部（60% MMD 72% FSHD）。在诊断组之间，手、腿、膝、踝和脚的疼痛强度存在显著差异，MMD患者C报告的这些部位的疼痛强度大于FSHD患者。年龄与疼痛的发作有关（在FSHD样本中，报告疼痛的参与者比未报告疼痛的参与者年轻），但疼痛严重程度与报告疼痛的年龄无关。有两种诊断的受访者报告了行动不便和使用辅助设备（如轮椅，手杖）报告的疼痛严重程度比那些行动不便的人谁没有使用辅助设备，谁，反过来。报告疼痛的严重程度比没有任何行动不便的受访者。据报道，提供最大的疼痛缓解的治疗不一定是那些最经常尝试或仍然used.Conclusions：研究结果表明，疼痛是一个更常见的问题，FSHD的人比MMD的人。尽管它在两个种群中都很常见。此外，这些疼痛问题是慢性的，强调需要确定并为这些神经肌肉疾病患者提供有效的疼痛治疗。
Objective: To determine the nature and scope of pain in working-aged adults with myotonic muscular dystrophy (MMD) and facioscapulohumeral muscular dystrophy (FSHD).Design: Retrospective, cross-sectional survey.Setting: Community-based survey.Participants: Convenience sample of subjects with MMD and FSHD.Interventions: Not applicable.Main Outcome Measures: Overall intensity and duration of pain. pain inference, pain sites, pain treatments, and relief provided by pain treatments.Results: More subjects with FSHD (82%) than with MMD (64%) reported pain. The most frequently reported pain sites for both diagnostic groups were lower back (66% MMD. 74% FSHD) and legs (60% MMD 72% FSHD). Significant differences in pain intensity were found between the diagnostic,Groups in the hands, leas, knees, ankles, and feet, with patients C with MMD reporting greater pain intensity at these sites than patients with FSHD. Age was related to the onset of pain (participants reporting pain were younger than those not reporting pain in the FSHD sample), but pain severity was not significantly associated with age in those reporting pain. Respondents with both diagnoses that reported mobility limitations and used assistive devices (eg, wheelchair, cane) reported more pain severity than those with mobility limitations who did not use assistive devices, who, in turn. reported more pain severity than respondents who reported no mobility limitations at all. The treatments that were reported to provide the greatest pain relief were not necessarily those that were the most frequently tried or still used.Conclusions: The findings indicate that pain is a more common problem in persons with FSHD than in persons with MMD. although it is common in both populations. In addition, these pain problems are chronic, underscoring the need to identify and provide effective pain treatments for patients with these neuromuscular diseases.