Outcome of postoperative pneumonia in the Eole study
Outcome of postoperative pneumonia in the Eole study
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DOI：
10.1007/s00134-002-1603-0
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发表时间：
2003-02-01
影响因子：
38.9
通讯作者：
Martin, C
中科院分区：
文献类型：
--
作者：
Dupont, H;Montravers, P;Martin, C
目的：呼吸机相关性肺炎（VAP）的预后因素研究较多，而术后肺炎（POP）的相关研究较少。这项多中心前瞻性研究的目的是评估POP死亡率的预测因素以及初始抗生素治疗对结局的影响。方法：纳入200个中心。POP的诊断进行了评估的临床和实验室标准，胸部X线变化和微生物标准，如果可能的话。记录患者的结局。一个独立的委员会对抗菌治疗的适当性进行了回顾性评估。结果：556例POP患者中，总死亡率为23%（126例）。五个参数与死亡率独立相关：美国麻醉学会（ASA）3级或以上（p
Objectives: Prognosis factors of ventilator-associated pneumonia (VAP) have been largely investigated, while the data concerning postoperative pneumonia (POP) are scarce. The aim of this multicenter, prospective study was to evaluate the predictive factors of mortality due to POP and the impact of initial antibiotic therapy on outcome. Methods: Two hundred centers were included. Diagnosis of POP was assessed on clinical and laboratory criteria, chest X-ray changes and microbiological criteria, when possible. Outcomes of the patients were noted. An independent committee made a retrospective assessment of appropriateness of antimicrobial therapy. Results: The overall mortality among the 556 cases of POP was 23% (126 patients). Five parameters were independently associated with mortality: American Society of Anesthesiology (ASA) grade 3 or more (p