Sexual differences in the distribution of epithelial alterations in vitamin A-deficient rats.
Sexual differences in the distribution of epithelial alterations in vitamin A-deficient rats.
复制标题
维生素 A 缺乏大鼠上皮改变分布的性别差异。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
D. Martin
中科院分区：
文献类型：
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作者：
Andres J Klein;J. Clark;D. Martin
维持维生素A缺乏饮食的雄性和雌性大鼠在几个病理特征中表现出性别相关的差异。男性比女性更早出现维生素A缺乏症的严重表现。他们还提出了更广泛的鳞状上皮化生的气管和更严重的涎腺炎，特别是颌下腺。另一方面，女性肾盂鳞状上皮化生较早且更广泛。这些病理特征中两性异形的根本原因尚不清楚，但建议受激素影响。
Male and female rats maintained on a vitamin A-deficient diet showed sex-related differences in several pathological features. Males developed severe manifestations of hypovitaminosis A earlier than females. They also presented more extensive squamous metaplasia of the trachea and more severe sialoadenitis, especially of the submaxillary gland. Females, on the other hand, presented earlier and more extensive squamous metaplasia of the renal pelvis. The underlying causes of sexual dimorphism in these pathological features are not known, but hormonal influences are suggested.