Polybrominated diphenyl ethers (PBDEs) in human serum from Southeast China.
Polybrominated diphenyl ethers (PBDEs) in human serum from Southeast China.
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DOI：
10.1016/j.ecoenv.2011.11.016
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发表时间：
2012-04
影响因子：
6.8
通讯作者：
Chunyan Wang;Zeng Lin;Q. Dong;Zhenkun Lin;Kuangfei Lin;Junxia Wang;Jianxiong Huang;Xuehui Huang;Yini He;Chenping Huang;Dongren Yang;Changjiang Huang
中科院分区：
文献类型：
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作者：
Chunyan Wang;Zeng Lin;Q. Dong;Zhenkun Lin;Kuangfei Lin;Junxia Wang;Jianxiong Huang;Xuehui Huang;Yini He;Chenping Huang;Dongren Yang;Changjiang Huang
多溴联苯醚（PBDEs）广泛用于电气电子产品中，但对电器厂工人和附近居民的暴露水平知之甚少。在这项研究中，我们评估了194名中国电器厂注射工人的多溴二苯醚身体负担，并测量了205份来自餐饮工人、皮革工厂工人、脐带和不育男性的血液样本进行比较。采用气相色谱-质谱法测定血清样品中的12个多溴二苯醚同系物。注射工人的总多溴二苯醚浓度最高，与工作时间呈正相关。BDE-209是最主要的同源基因，其次是BDE-47、28和99。我们还发现脐带血中存在所有12种多溴二苯醚，这表明胎儿暴露的证据。与餐饮工人和皮革工厂工人相比，不育男性血清样本中BDE-47的浓度尤其高。
Polybrominated diphenyl ethers (PBDEs) have been used extensively in electrical and electronic products, but little is known about the exposure level in the electrical appliance factories workers and nearby local residents. In this study, we assessed body burdens of PBDEs in 194 Chinese injection workers from electrical appliance factories and also measured 205 blood samples from catering workers, leather factory workers, umbilical cord and infertile men for comparison. Twelve PBDE congeners in serum samples were measured by GC–MS. The highest concentration for total PBDEs was found in injection workers, which is positively correlated to employment duration. BDE-209 was the most dominant congener followed by BDE-47, 28 and 99. We also found the presence of all twelve PBDEs in cord blood, suggesting an evidence of fetal exposure. Concentration of BDE-47 was particularly higher in serum samples from infertile men in comparison with that of catering workers and leather factory workers.