Synthesis and characterization of small circular double-stranded RNAs
Synthesis and characterization of small circular double-stranded RNAs
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DOI：
10.1039/c0cc04551a
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发表时间：
2011-01-01
影响因子：
4.9
通讯作者：
Ito, Yoshihiro
中科院分区：
文献类型：
--
作者：
Abe, Naoko;Abe, Hiroshi;Ito, Yoshihiro
合成小的环状双链RNA（dsRNA）。通过原子力显微镜的结构分析给出了用于解释环状dsRNA中存在的结构应变的直接图像。最后，我们证明了环状dsRNA在细胞中引起RNAi效应。
Small circular double-stranded RNAs (dsRNAs) were synthesized. The structural analysis by atomic force microscopy gave direct images for the interpretation of the structural strain present in circular dsRNAs. Finally, we demonstrated that circular dsRNA caused RNAi effect in cells.