N→S Acyl-Transfer-Mediated Synthesis of Peptide Thioesters Using Anilide Derivatives
N→S Acyl-Transfer-Mediated Synthesis of Peptide Thioesters Using Anilide Derivatives
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DOI：
10.1021/ol8028093
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发表时间：
2009-02-19
期刊：
影响因子：
5.2
通讯作者：
Otaka, Akira
中科院分区：
文献类型：
--
作者：
Tsuda, Shugo;Shigenaga, Akira;Otaka, Akira
已经检查了利用N-氨酰基-N-硫烷基乙基氨基苯甲酸衍生物的肽硫酯的N -> S酰基转移介导的合成。开发的肽硫酯合成方法与Fmoc固相肽合成（SPPS）兼容。
N -> S acyl-transfer-mediated synthesis of peptide thioesters utilizing an N-aminoacyl-N-sulfanylethylaminobenzoic acid derivative has been examined. The developed synthetic methodology for peptide thioesters is compatible with Fmoc solid-phase peptide synthesis (SPPS).