Growth curves of myopia-related parameters to clinically monitor the refractive development in Chinese schoolchildren
Growth curves of myopia-related parameters to clinically monitor the refractive development in Chinese schoolchildren
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DOI：
10.1007/s00417-019-04290-6
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发表时间：
2019-05-01
影响因子：
2.7
通讯作者：
Ohlendorf, Arne
中科院分区：
文献类型：
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作者：
Diez, Pablo Sanz;Yang, Li-Hua;Ohlendorf, Arne
目的 建立基于武汉地区学龄儿童眼轴长度百分位数曲线的近视发展预测临床模型。方法收集并分析 12,554 名儿童（6054 名女孩和 6500 名男孩）的眼轴长度增长曲线的生成数据。第二个数据集包含 226 名儿童和三年连续测量，用于验证眼轴生长百分位曲线的预测能力。计算了两个性别组和四个年龄组（6、9、12 和 15 岁）的百分位数曲线。第二个数据集用于验证根据第三次就诊的球面屈光不正，使用眼轴曲线识别儿童屈光不正的有效性。结果从 6 岁到 15 岁，所有百分位数都显示眼轴长度增长趋势，除了第一四分位数以下的百分位数在 12 岁后趋于稳定（-0.10；95%CI， -0.36-0.16；女孩 P = 0.23； -0.16； 95%置信区间，-0.70-0.39；男孩 P = 0.34）；然而，其余 75% 的病例仍在继续增长。第二组数据显示，患高度近视（球面屈光不正）的可能性
Purpose To produce a clinical model for the prediction of myopia development based on the creation of percentile curves of axial length in school-aged children from Wuhan in central China.Methods Data of 12,554 children (6054 girls and 6500 boys) were collected and analyzed for the generation of the axial length growth curves. A second data set with 226 children and three yearly successive measurements was used to verify the predictive power of the axial length growth percentile curves. Percentile curves were calculated for both gender groups and four age groups (6, 9, 12, and 15years). The second data set was used to verify the efficacy of identifying the refractive error of the children using the axial length curves, based on their spherical refractive error from the third visit.Results From 6 to 15years of age, all percentiles showed a growth trend in axial length, except for the percentiles below the first quartile, which appear to stabilize after the age of 12 (-0.10; 95%CI, -0.36-0.16; P = 0.23 for girls; -0.16; 95%CI, -0.70-0.39; P = 0.34 for boys); however, the growth continued for the remaining 75% of cases. The second data set showed that the likelihood of suffering high myopia (spherical refractive error