Articular cartilage: Injuries and potential for healing
Articular cartilage: Injuries and potential for healing
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DOI：
10.2519/jospt.1998.28.4.192
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发表时间：
1998-10-01
影响因子：
6.1
通讯作者：
Buckwalter, JA
中科院分区：
文献类型：
--
作者：
Buckwalter, JA
冲击和扭转关节负荷可损伤关节软骨，引起疼痛、关节功能障碍和积液，并且在某些情况下，进行性关节退化。损伤类型和修复反应的差异区分了三类关节面损伤：I）关节面损伤，其使关节面保持完整，但引起内部软骨损伤并可能引起软骨下骨损伤，2）关节面的机械破坏限于关节软骨，以及3）关节软骨和软骨下骨的机械破坏。各种治疗方法都有可能改善关节面的愈合，包括软骨下骨穿孔、关节负荷改变、骨膜和软骨膜移植、细胞移植、生长因子和人工基质。关节软骨损伤患者的治疗选择应根据对损伤类型、愈合潜力以及治疗对关节表面恢复的影响的理解来指导。
Impact and torsional joint loading can injure articular cartilage, causing pain, joint dysfunction and effusions, and, in some instances, progressive joint degeneration. Differences in the type of injury and the repair response distinguish three classes of articular surface injuries: I) damage to the joint surface that leaves the articular surface intact but causes internal chondral damage and may cause subchondral bone injury, 2) mechanical disruption of the articular surface limited to articular cartilage, and 3) mechanical disruption of articular cartilage and subchondral bone. A variety of treatments has the potential to improve healing of articular surfaces, including perforation of subchondral bone, altered joint loading, periosteal and perichondrial grafts, cell transplantation, growth factors, and artificial matrices. Selection of treatment for a patient with an articular cartilage injury should be guided by an understanding of the type of injury, the potential for healing, and the effects of treatment on joint surface restoration.