Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit (PREBIS study data)
Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit (PREBIS study data)
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DOI：
10.1111/acps.12003
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发表时间：
2013-05-01
影响因子：
6.7
通讯作者：
Vieta, E.
中科院分区：
文献类型：
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作者：
Grande, I.;Goikolea, J. M.;Vieta, E.
Grande I, Goikolea JM, de Dios C, Gonzalez-Pinto A, Montes JM, Saiz-Ruiz J, Prieto E, Vieta E， PREBIS组。双相情感障碍的职业残疾：严重残疾获益的预测因素分析（PREBIS研究数据）。目的：据报道，双相情感障碍（BD）患者在发作间期有明显的工作障碍。本研究旨在通过对身心健康患者的纵向随访，评估职业残疾的潜在预测因素。方法：我们纳入了327例诊断为I型或II型双相障碍的健康患者，其中226例就业，101例接受严重残疾福利（SDB）。研究了社会人口学数据，并在1年随访期间评估了复发情况。采用Logistic回归分析确定SDB的预测因素。建立了Cox回归来研究递归。结果：患SDB的预测因子为：II轴共病[比值比(OR)=2.94, CI: 1.266.86， P=0.013]、躁狂发作次数(OR=1.21, CI: 1.101.34， P=0.013]
Grande I, Goikolea JM, de Dios C, Gonzalez-Pinto A, Montes JM, Saiz-Ruiz J, Prieto E, Vieta E, for the PREBIS group. Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit PREBIS study data). Objective: Patients diagnosed with bipolar disorder (BD) are reported to have significant work impairment during interepisode intervals. This study was carried out to assess potential predictors of occupational disability in a longitudinal follow-up of euthymic patients. Method: We included 327 euthymic patients diagnosed with BD type I or type II, 226 of whom were employed and 101 were receiving a severe disablement benefit (SDB). Sociodemographic data were studied and episode recurrence was assessed along a 1-year follow-up. Logistic regression analysis was applied to determine predictors of receiving SDB. Cox regression was built to study recurrences. Results: Predictors of receiving SDB were: axis II comorbidity [Odds Ratio (OR)=2.94, CI: 1.266.86, P=0.013], number of manic episodes (OR=1.21, CI: 1.101.34, P