A comparison of skeletal maturity and growth
A comparison of skeletal maturity and growth
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DOI：
10.3109/03014460.2012.756122
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发表时间：
2013-07-01
影响因子：
1.7
通讯作者：
Largo, Remo
中科院分区：
文献类型：
--
作者：
Molinari, Luciano;Gasser, Theo;Largo, Remo
背景资料：体细胞和骨骼的发展都进行了详细的研究，但很少在congression.Aim：本研究的目的是确定什么样的体细胞和骨骼的发展有共同点，以及它们如何不同。第二个目标是检查骨龄（BA）的青春期突升，并以类似于身高的方式对其进行量化。Preece-Baines模型是用来拟合纵向数据BA。科目和方法：分析的数据是从第一苏黎世纵向生长研究，包括120名男孩和112名女孩几乎完整的数据从出生到adult.Results：变异的躯体里程碑减少BA和有一个aftergrowth后，达到成人罗斯得分1000。罗斯评分在青春期冲刺期（PS）的晚期显著增加。躯体里程碑与这些年龄段获得的罗斯评分相关，在PS早期更是如此。BA的PS被明确确定为男孩14.2岁，女孩12.2岁。年龄的峰值骨发育与年龄的峰值速度的躯体variable.Conclusions：BA可以成功地建模为一个半定量的实体。骨发育与躯体发育有明显的相关性，尽管后者反映了大小的变化，而前者基本上是一个成熟指数，反映了组织生化组成的变化。
Background: Somatic and bone development have each been studied in detail, but rarely in conjunction.Aim: The aim of this study was to determine what somatic and bone development have in common and how they differ. A second aim was to check for a pubertal spurt in bone age (BA) and to quantify it in a similar way as has been done for height. The Preece-Baines model is used to fit longitudinal data for BA.Subjects and methods: The data analysed are from the 1st Zurich Longitudinal Growth Study comprising 120 boys and 112 girls with almost complete data from birth to adulthood.Results: Variability of somatic milestones was reduced in terms of BA and there was an aftergrowth after reaching adult RUS score 1000. A strong increase in the RUS score was seen at a late stage of the pubertal spurt (PS). Somatic milestones correlated with the RUS score attained at these ages and more so at an early stage of the PS. A PS for BA was clearly identified with a location at 14.2 years for boys and 12.2 years for girls. Age of peak bone development correlated highly with age of peak velocity of somatic variables.Conclusions: BA can be successfully modelled as a semi-quantitative entity. Bone development shows marked associations with somatic development, despite the fact that the latter reflects changes in size, while the former is essentially a maturity index and reflects changes in biochemical composition of tissues.