A Chromatographic Study of Hematoporphyrin Derivatives

A Chromatographic Study of Hematoporphyrin Derivatives
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血卟啉衍生物的色谱研究

DOI:
10.1007/978-1-4684-4721-7_9
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发表时间:
1984
期刊:
Progress in clinical and biological research
影响因子:
--
通讯作者:
J. Evensen
J. Evensen
中科院分区:
--
文献类型:
--
作者:
S. Sommer;J. Moan;T. Christensen;J. Evensen

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血卟啉衍生物(Hematoporphyrin derivative,Hpd)是Lipson等首次提出的一种卟啉混合物,是目前临床应用最广泛的肿瘤光放射治疗药物。此外,由于其荧光和肿瘤定位特性,它可用于癌症诊断1 -5。血卟啉衍生物中各组分具有不同的肿瘤定位和光敏特性,应对其进行表征,以筛选出最佳的组分用于临床和进一步研究。
Hematoporphyrin derivative (Hpd), a porphyrin mixture first introduced as a tumorlocalizer by Lipson et al. is the most widely used drug in clinical trials for photoradiation therapy (PRT) of cancer. Furthermore, due to its fluorescence and tumorlocalizing properties, it may be used in cancer diagnosis1–5. The components in Hpd have different tumorlocalizing and photosensitizing properties which should be characterized in order to select the component with the best properties for clinical use and for further investgations.
DOI: --
发表时间: 1982
期刊: Mayo Clinic proceedings. Mayo Clinic
影响因子: --
作者:
BensonJr,RC;Farrow,GM;Kinsey,JH;Cortese,DA;Zincke,H;Utz,DC
通讯作者: Utz,DC
血卟啉衍生物的成分及其肿瘤定位能力。
DOI: --
发表时间: 1982
期刊: Cancer research
影响因子: 11.2
作者:
Kessel,D
通讯作者: Kessel,D