Liquid Marbles in Liquid
Liquid Marbles in Liquid
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液体中的液体弹珠
DOI：
10.1002/smll.202002802
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发表时间：
2020
期刊：
影响因子：
13.3
通讯作者：
Wang Steven
中科院分区：
文献类型：
--
作者：
Zhao Zhijian;Ling Chen;Wang Dan;Wang Jie-Xin;Saczek Joshua;Pramana Stevin;Sridhar Sreepathy;Shang Jin;Xu Ben B.;Tsang Daniel C. W.;Chen Jian-Feng;Wang Steven
传统的液体球（LMs），即在气液界面处被疏水颗粒包裹的液滴，由于其寿命短和传热效率低而受到限制。在此，设计了一种用于浸没在各种液体介质中的LM的新范例，其具有大规模增强的传热和空间识别;与空气中的经典LM或有机试剂中的裸液滴相比，在不损害结构完整性的情况下，液体中的液体弹珠（LMIL）的寿命延长了1000倍。在外部刺激下，LMIL显示出有希望的反向结构重构能力，并在很长一段时间（10周）内保持其功能。这些上级性能被进一步开发为具有延长寿命和优异温度控制的微型反应器，结合其可行的操作，将在先进化学和生物医学工程领域开辟新的机会。研究还表明，LMIL可用于亚甲基蓝降解和3D体外酵母细胞培养。这些发现对LMs在真实的世界中的应用具有重要意义，在细胞培养技术、液滴实验室、聚合、封装、配制和药物递送中具有许多应用。
Traditional liquid marbles (LMs), liquid droplets encapsulated by hydrophobic particles at the liquid–gas interface, are restricted by their short lifetime and low heat transfer efficiency. Herein, a new paradigm for LMs immersed in various liquid mediums with massive enhanced heat transfer and spatial recognition is designed; without compromising the structural integrity, the lifetime of the liquid marbles in liquid (LMIL) is extended by ≈1000 times compared to classical LMs in air or naked droplets in organic reagents. The LMIL shows promising reverse structural re‐configurability while under external stimuli and maintaining their functionality for a very long period of time (≈weeks). These superior behaviors are further exploited as a miniature reactor with prolonged lifetimes and excellent temperature control, combined with its feasible operation, new opportunities will open up in the advanced chemical and biomedical engineering fields. It is also shown that LMIL can be applied in methylene blue degradation and 3D in‐vitro yeast cell cultures. These findings have important implications for real‐world use of LMs, with a number of applications in cell culture technology, lab‐in‐a‐drop, polymerization, encapsulation, formulation, and drug delivery.