Glycerophosphodiester phosphodiesterase gene (glpQ) of Borrelia lonestari identified as a target for differentiating Borrelia species associated with hard ticks (Acari:Ixodidae)

Glycerophosphodiester phosphodiesterase gene (glpQ) of Borrelia lonestari identified as a target for differentiating Borrelia species associated with hard ticks (Acari:Ixodidae)
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DOI:
10.1128/jcm.42.5.2326-2328.2004
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发表时间:
2004-05-01
影响因子:
9.4
通讯作者:
Schwan, TG
Schwan, TG
中科院分区:
医学2区
文献类型:
--
作者:
Bacon, RM;Pilgard, MA;Schwan, TG

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在隆氏疏螺旋体阳性的美洲Amblyomma americanum的DNA中发现了glpQ同源基因,这进一步证明了隆氏疏螺旋体与复发热组螺旋体的关系比与导致莱姆病的疏螺旋体更密切。这一发现为发展诊断试验以区分由硬蜱传播的疏螺旋体提供了基础。
A glpQ ortholog was identified in DNA from Borrelia lonestari-positive Amblyomma americanum, providing further evidence that B. lonestari is more closely related to the relapsing fever group spirochetes than to borreliae that cause Lyme disease. This finding provides a basis for developing diagnostic assays to differentiate species of borrelia transmitted by hard ticks.