Lens opacity, thickness, and position in subjects with acute primary angle closure
Lens opacity, thickness, and position in subjects with acute primary angle closure
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DOI：
10.1097/01.ijg.0000212212.10395.76
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发表时间：
2006-06-01
影响因子：
2
通讯作者：
Aung, Tin
中科院分区：
文献类型：
--
作者：
Lim, Marcus C. C.;Lim, Laurence S.;Aung, Tin
目的：比较急性初级闭角术（APAC）患者的晶状体厚度（LT）、晶状体位置（LP）、相对晶状体位置（RLP）以及晶状体混浊的程度和类型，以确定晶状体特征的任何差异，这些差异可能导致急性发作。此外，测量轴向长度（AL）和前房深度（ACD）。方法：对73例单侧APAC患者进行双眼激光虹膜切开术治疗。术后2周采用超声测厚法测量双眼ACD、LT和AL。LP定义为ACD + (2)/(LT)-L-1， RLP定义为LP/AL。晶状体不透明度分级III （LOCS III）系统用于晶状体不透明度分级。结果：受试者中90%为中国人，63%为女性。平均年龄61.0±10.9岁。受影响的眼睛和其他眼睛在ACD （2.11 +/- 0.35 vs 2.18 +/- 0.23, P = 0.02）和LP （4.61 +/- 0.47 vs 4.75 +/- 0.29, P = 0.02）方面存在显著差异。同组眼睛的皮质混浊更大（0.32 +/- 0.72 vs 0.53 +/- 0.95; P = 0.02）。在核区和后囊下区，LT、RLP或晶状体混浊程度没有差异。结论：与正常眼相比，apac影响眼的ACD较浅，前LP较多，皮质混浊较少。这些差异可能有助于亚太地区。
Purpose: To compare lens thickness (LT), lens position (LP), relative lens position (RLP), and degree and type of lens opacity between affected and fellow eyes of subjects with acute primary angle closure (APAC) to identify any differences in lens characteristics that may be contributory to the acute episode. In addition, axial length (AL) and anterior chamber depth (ACD) measurements were evaluated.Methods: Seventy-three study subjects with unilateral APAC were treated with sequential laser iridotomy (LI) in both eyes. Two weeks after LL ACD, LT, and AL measurements were made in both eyes using ultrasound pachymetry. LP was defined as ACD + (2)/(LT)-L-1 and RLP as LP/AL. The Lens Opacity Classification III (LOCS III) System was used for grading lens opacity.Results: The subjects were 90% Chinese and 63% female. Mean age was 61.0 +/- 10.9 years. Significant differences between the affected and fellow eyes were found in the ACD (2.11 +/- 0.35 vs 2.18 +/- 0.23; P = 0.02) and LP (4.61 +/- 0.47 vs 4.75 +/- 0.29; P = 0.02). Cortical opacity was greater in fellow eyes (0.32 +/- 0.72 vs 0.53 +/- 0.95; P = 0.02). There was no difference in LT, RLP, or degree of lens opacity in the nuclear and posterior subcapsular regions.Conclusions: Compared with fellow eyes, APAC-affected eyes have shallower ACD, more anterior LP, and less cortical opacity. These differences may be contributory to APAC.