Measurement of fatigue in cancer patients: development and validation of the Fatigue Symptom Inventory

Measurement of fatigue in cancer patients: development and validation of the Fatigue Symptom Inventory
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DOI:
10.1023/a:1024929829627
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发表时间:
1998-05-01
影响因子:
3.5
通讯作者:
Lyman, G
Lyman, G
中科院分区:
医学2区
文献类型:
--
作者:
Hann, DM;Jacobsen, PB;Lyman, G

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尽管疲劳是癌症患者最常见、最令人衰弱的症状之一,但它很少受到系统的关注。这种情况在很大程度上是由于缺乏足够的仪器来测量疲劳。本研究的主要目的是验证一种新开发的用于癌症患者的疲劳测量方法:疲劳症状量表 (FSI)。这项包含 13 项的自我报告测量旨在测量疲劳的强度和持续时间及其对生活质量的影响。在接受乳腺癌治疗的女性、已完成乳腺癌治疗的女性和没有癌症病史的女性中评估了 FSI 的心理测量特性。七项干扰分量表具有良好的内部一致性,所有三组的系数均高于 0.90。研究发现,在积极治疗的患者和在三个不同场合评估的健康对照受试者中,完整的 FSI 具有相当弱到中等的重测可靠性。通过与现有的疲劳测量方法进行比较,证明了收敛有效性。通过组间和组内比较以及与焦虑和抑郁测量的比较来证明结构有效性。总体而言,FSI 被确立为癌症患者和健康个体疲劳的有效且可靠的衡量标准。对该措施在临床研究中的潜在应用提出了建议。 (C) 1998 年利平科特-乌鸦出版社。
Although fatigue is one of the most common and debilitating symptoms experienced by cancer patients, it has received little systematic attention. This situation is due in large part to the lack of adequate instruments to measure fatigue. The primary aim of this study was to validate a newly developed measure of fatigue for use with cancer patients: the Fatigue Symptom Inventory (FSI). This 13 item self-report measure was designed to measure the intensity and duration of fatigue and its impact on quality of life. The psychometric properties of the FSI were assessed in women undergoing treatment for breast cancer, women who had completed treatment for breast cancer and women with no history of cancer. A seven-item interference subscale was found to have good internal consistency, with a coefficients above 0.90 in all three groups. The complete FSI was found to have rather weak to moderate test-retest reliability among patients in active treatment and healthy comparison subjects assessed on three separate occasions. Convergent validity was demonstrated using comparisons with existing measures of fatigue. Construct validity was demonstrated using comparisons between and within groups as well as comparisons with measures of anxiety and depression. Overall, the FSI was established as a valid and reliable measure of fatigue in cancer patients and healthy individuals. Suggestions are made for the potential application of the measure in clinical research. (C) 1998 Lippincott-Raven Publishers.