Reproducibility of peak oxygen uptake and other cardiopulmonary exercise testing parameters in patients with heart failure (from the Heart Failure and A Controlled Trial Investigating Outcomes of exercise traiNing)
Reproducibility of peak oxygen uptake and other cardiopulmonary exercise testing parameters in patients with heart failure (from the Heart Failure and A Controlled Trial Investigating Outcomes of exercise traiNing)
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DOI：
10.1016/j.amjcard.2008.04.047
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发表时间：
2008-09-15
影响因子：
2.8
通讯作者：
Russell, Stuart D.
中科院分区：
文献类型：
--
作者：
Bensimhon, Daniel R.;Leifer, Eric S.;Russell, Stuart D.
最大摄氧量（pVo（2））是评价心力衰竭患者功能和预后的重要指标。在心力衰竭试验中，pVo（2）的变化通常用于评估干预措施的有效性。然而，pVo（2）在系列测试中的受试者内变异性可能会限制其有用性。本研究旨在评价pVo（2）在2次基线心肺运动试验中的受试者内变异性。作为HF-ACTION试验的子研究，398例心力衰竭和左心室射血分数> 1的受试者（73%男性，27%女性;平均年龄59岁）基线心肺运动试验。(C)2008年爱思唯尔公司All rights reserved.
Peak oxygen uptake (pVo(2)) is an important parameter in assessing the functional capacity and prognosis of patients with heart failure. In heart failure trials, change in pVo(2) was often used to assess the effectiveness of an intervention. However, the within-subject variability of pVo(2) on serial testing may limit its usefulness. This study was designed to evaluate the within-subject variability of pVo(2) over 2 baseline cardiopulmonary exercise tests. As a substudy of the HF-ACTION trial, 398 subjects (73% men, 27% women; mean age 59 years) with heart failure and left ventricular ejection fraction 1 baseline cardiopulmonary exercise test. (C) 2008 Elsevier Inc. All rights reserved.