Determination of fipronil and its metabolites in environmental water samples by meltblown nonwoven fabric‐based solid‐phase extraction combined with gas chromatography‐electron capture detection
Determination of fipronil and its metabolites in environmental water samples by meltblown nonwoven fabric‐based solid‐phase extraction combined with gas chromatography‐electron capture detection
复制标题
熔喷非织造布固相萃取-气相色谱-电子捕获检测法测定环境水样中氟虫腈及其代谢物
DOI：
10.1002/jssc.202200008
复制
发表时间：
2022
影响因子：
3.1
通讯作者：
Jin-Jie Yang
中科院分区：
文献类型：
--
作者：
Qin Zhao;Shi-Wen Yue;Yi-Lian Zhou;Jin-Jie Yang
本研究建立了一种基于熔喷无纺布固相萃取-气相色谱-电子捕获检测的环境水样中氟虫腈及其3种代谢物的检测新方法。熔喷非织造布是医用口罩的核心材料，由聚丙烯超细纤维随机分布粘合而成，具有较大的比表面积和良好的透气性。聚丙烯作为一种高分子烃基聚合物，具有良好的疏水性和亲脂性等特点，可用于食品、环境、生物样品中疏水物质的分离富集。熔喷非织造布柔软，能紧密填充固相萃取筒。这也使其成为理想的固相萃取吸附剂。考察了影响提取效率的一系列参数，在优化条件下，氟虫腈及其3种代谢物在0.2 ~ 100 μg/L范围内呈良好的线性关系，相关系数R2 > 0.999。加标回收率在99.2 ~ 107.3%范围内，日内相对标准偏差小于9.8%，日内相对标准偏差小于8.1%。4种目标物的检出限在0.02 ~ 0.06 μg/L范围内。最后，该方法成功应用于各类环境水样中氟虫腈及其三种代谢物的分析。
In this study, a new method for the determination of fipronil and its three metabolites in environmental water samples was developed based on meltblown nonwoven fabric solid-phase extraction combined with gas chromatography-electron capture detection. As the core material of medical masks, meltblown nonwoven fabric is made of polypropylene superfine fibers which are randomly distributed and bonded together with a relatively large specific surface area and good permeability. Polypropylene as a high molecular hydrocarbon-based polymer has the characteristics of good hydrophobicity and lipophilicity, which can be applied for the separation and enrichment of hydrophobic substances in food, environment, and biological samples. The meltblown nonwoven fabric is soft and can fill the solid-phase extraction cartridge tightly. This aspect also makes it suitable to be used as an ideal solid-phase extraction sorbent. A series of parameters influencing the extraction efficiency were investigated, and under the optimized conditions, fipronil and its three metabolites had a good linear relationship in the range of 0.2-100 μg/L with a correlation coefficient R2 of more than 0.999. The recoveries at three spiked concentrations were in the range of 99.2-107.3% with the relative standard deviations less than 9.8% (intra-day) and 8.1% (inter-day). The limit of detection for the four target analytes was in the range of 0.02-0.06 μg/L. Finally, this method was successfully applied in the analysis of fipronil and its three metabolites in various types of environmental water samples.