A New Beneficial Mutation in Pseudomonas sp. 61-3 Polyhydroxyalkanoate (PHA) Synthase for Enhanced Cellular Content of 3-Hydroxybutyrate-Based PHA Explored Using Its Enzyme Homolog as a Mutation Template
A New Beneficial Mutation in Pseudomonas sp. 61-3 Polyhydroxyalkanoate (PHA) Synthase for Enhanced Cellular Content of 3-Hydroxybutyrate-Based PHA Explored Using Its Enzyme Homolog as a Mutation Template
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DOI：
10.1271/bbb.100224
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发表时间：
2010-08
期刊：
影响因子：
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通讯作者：
Fumi Shozui;Jian Sun-;Yuyang Song;Miwa Yamada;Kohei Sakai;Ken’ichiro Matsumoto;K. Takase;S. Taguchi
中科院分区：
文献类型：
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作者：
Fumi Shozui;Jian Sun-;Yuyang Song;Miwa Yamada;Kohei Sakai;Ken’ichiro Matsumoto;K. Takase;S. Taguchi
发现一个新分离的突变（Gln 508 Leu）及其与先前发现的来自假单胞菌61-3的聚羟基链烷酸合酶1中的有益突变的组合增强了重组大肠杆菌中聚（3-羟基丁酸酯）[P（3 HB）]和聚（3 HB-co-3-羟基链烷酸酯）的产生。
A newly isolated mutation (Gln508Leu) and a combination of it with previously discovered beneficial mutations in polyhydroxyalkanoate synthase 1 from Pseudomonas sp. 61-3 were found to enhance the production of poly(3-hydroxybutyrate) [P(3HB)] and poly(3HB-co-3-hydroxyalkanoate)s in recombinant Escherichia coli.