EVOLUTIONARY ORIGIN OF PLASMODIUM AND OTHER APICOMPLEXA BASED ON RIBOSOMAL-RNA GENES
EVOLUTIONARY ORIGIN OF PLASMODIUM AND OTHER APICOMPLEXA BASED ON RIBOSOMAL-RNA GENES
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DOI：
10.1073/pnas.92.13.5793
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发表时间：
1995-06-20
影响因子：
11.1
通讯作者：
AYALA, FJ
中科院分区：
文献类型：
--
作者：
ESCALANTE, AA;AYALA, FJ
我们通过比较小亚基核糖体RNA基因的核苷酸序列，探索了顶复门和两个相关的原生生物门恐龙门和纤毛门的进化历史，我们得出结论，疟疾寄生虫所属的疟原虫谱系与其他顶复门谱系（梨质体和球虫）有数百个分歧。 万年前，甚至可能早于寒武纪。疟原虫辐射产生于大约 1.29 亿年前，导致了多种人类寄生物种的产生。人类的疟原虫寄生已独立出现过数次，顶端复虫（疟原虫）、甲藻和纤毛虫的起源可能>10亿年，或许比动物、植物和真菌这三个多细胞王国还要古老，双遗传寄生独立；在顶端复合体中进化了几次。
We have explored the evolutionary history of the Apicomplexa and two related protistan phyla, Dinozoa and Ciliophora, by comparing the nucleotide sequences of small subunit ribosomal RNA genes, We conclude that the Plasmodium lineage, to which the malarial parasites belong, diverged from other apicomplexan lineages (piroplasmids and coccidians) several hundred million years ago, perhaps even before the Cambrian. The Plasmodiun radiation, which gave rise to several species parasitic to humans, occurred approximate to 129 million years ago; Plasmodium parasitism of humans has independently arisen several times, The origin of apicomplexans (Plasmodium), dinoflagellates, and ciliates may be >1 billion years old, perhaps older than the three multicellular kingdoms of animals, plants, and fungi, Digenetic parasitism independently; evolved several times in the Apicomplexa.