Effects of maternal smoking upon neuropsychological development in early childhood: importance of taking account of social and environmental factors.
Effects of maternal smoking upon neuropsychological development in early childhood: importance of taking account of social and environmental factors.
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DOI：
10.1111/j.1365-3016.1992.tb00784.x
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发表时间：
1992-10-01
影响因子：
2.8
通讯作者：
McMichael, A J
中科院分区：
文献类型：
--
作者：
Baghurst, P A;Tong, S L;McMichael, A J
对548名从出生到4岁的儿童进行了前瞻性研究，以确定母亲在怀孕期间和/或怀孕后吸烟是否会影响儿童的神经心理发育。母亲吸烟的儿童与母亲不吸烟的儿童之间的平均发育测试分数差异很小，母亲吸烟的儿童的子量表分数仅低2.4%至4.1%。这些差异在调整社会经济地位，家庭环境质量和母亲的智力后没有统计学意义，这表明社会和环境因素是暴露于母亲吸烟和儿童期神经心理发育的主要混杂因素。为了更好地了解这一领域，将需要更精确的措施暴露于环境烟草烟雾和综合考虑混杂因素。
Data from a prospective study of 548 children followed from birth to 4 years of age were analysed to determine whether maternal smoking during and/or after pregnancy affects children's neuropsychological development. The differences in mean developmental test scores between children whose mothers smoked and those of mothers who did not smoke were slight, with subscale scores only 2.4 to 4.1% lower in children whose mothers smoked. These differences were not statistically significant after adjustment for socio-economic status, quality of home environment and mother's intelligence, suggesting that the social and environmental factors are major confounders of the association of exposure to maternal smoking and neuropsychological development in childhood. In order to gain a better understanding of this area, more precise measures of exposure to environmental tobacco smoke and comprehensive consideration of confounders will be required.