Poorly differentiated, solid-type adenocarcinoma of the stomach.
Poorly differentiated, solid-type adenocarcinoma of the stomach.
复制标题
低分化、实性胃腺癌。
DOI：
10.3109/03009739909178964
复制
发表时间：
1999
影响因子：
3.4
通讯作者：
H. Yamauchi
中科院分区：
文献类型：
--
作者：
T. Yokota;Y. Kunii;T. Saito;S. Teshima;Y. Yamada;M. Takahashi;S. Kikuchi;H. Yamauchi
本文回顾了我院1985 ~ 1995年收治的58例胃低分化实性腺癌的临床资料，并与146例胃非实性腺癌作了比较，以探讨两者的临床病理特点。在肿瘤大小、分期、大体外观、浸润深度、组织学生长模式、淋巴结转移、显微镜下淋巴管浸润和血管浸润方面观察到显著差异。实体型癌症组的患者倾向于肿瘤较小; 48%的患者处于早期阶段，58例患者中仅20例进行了全胃切除术。实体型癌症患者中淋巴结受累、淋巴管浸润和血管渗透也不太常见。实体型癌患者的总生存率高于非实体型癌患者，尽管在校正分期后没有观察到显著差异。我们的研究结果表明，低分化实体型胃癌应被视为一种独特的腺癌，有良好的预后。淋巴管侵犯和肿瘤位置是影响胃癌预后的重要因素。
Data of 58 cases of poorly differentiated, solid-type adenocarcinoma of the stomach treated at our hospital between 1985 and 1995 were reviewed and compared to data of 146 cases of non-solid-type carcinoma in order to determine whether there are distinguishable clinicopathological features between these two types of carcinoma. Significant differences were observed with respect to tumor size, stage, macroscopic appearance, depth of invasion, histologic growth pattern, lymph node metastasis, microscopical lymphatic invasion and vascular permeation. Patients in the solid-type cancer group tended to have smaller tumors; the disease was in the early stage in 48% of the patients, and total gastrectomy was performed in only 20 of the 58 patients. Nodal involvement, lymphatic invasion and vascular permeation were also less common in patients with solid-type cancer. The overall survival rate of patients with solid-type carcinoma was higher than that of patients with non-solid-type carcinoma, though no significant differences were observed when corrected for stage. Our results suggest that poorly differentiated solid-type carcinoma of the stomach should be regarded as a distinct type of adenocarcinoma that has a good prognosis. The significant prognostic factors for this type of gastric cancer are lymphatic invasion and tumor location.