A role for cellular senescence in birth timing
A role for cellular senescence in birth timing
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DOI：
10.1080/15384101.2017.1371888
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发表时间：
2017-01-01
期刊：
影响因子：
4.3
通讯作者：
Aronoff, David M.
中科院分区：
文献类型：
--
作者：
Cha, Jeeyeon M.;Aronoff, David M.
衰老导致组织的局部和全身老化，并与年龄相关疾病有关。最近，这一过程在妊娠期间的作用已被发现，其失调与不良妊娠结局（如早产）有关。在这里，我们总结了最近的进展，支持衰老在出生时间的作用，并提出了在这个新兴领域的研究的新方面。
Senescence contributes to the local and systemic aging of tissues and has been associated with age-related diseases. Recently, roles for this process during pregnancy have come to light, the dysregulation of which has been associated with adverse pregnancy outcomes such as preterm birth. Here, we summarize recent advances that support a role for senescence in birth timing and propose new aspects of study in this emerging field.