Causes of perinatal mortality and associated maternal complications in a South African province: challenges in predicting poor outcomes

Causes of perinatal mortality and associated maternal complications in a South African province: challenges in predicting poor outcomes
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DOI:
10.1186/s12884-015-0472-9
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发表时间:
2015-02-15
影响因子:
3.1
通讯作者:
Pattinson, Robert C.
Pattinson, Robert C.
中科院分区:
医学3区
文献类型:
--
作者:
Allanson, Emma R.;Muller, Mari;Pattinson, Robert C.

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背景:对围产儿死亡的综述大多是基于设施的。考虑到全球范围内在设施外分娩的女性人数,这一数据可能对总人口数据有偏见。我们的目的是分析南非姆普马兰加省基于人口的围产期死亡率数据,以确定围产期死亡的原因和围产期并发症的发生率。方法:对2013年10月至2014年1月期间南非穆普马兰加省的围产期问题识别计划(PPIP)数据库进行二次分析。回顾了每一例晚期围产儿死亡的数据。我们检查了晚期胎儿死亡中母亲和胎儿或新生儿特征的频率,并分析了产妇状况与胎儿和/或新生儿结局之间的关系。结果:研究期间共发生新生儿23503例,晚期围产儿死亡687例(死胎=1000gr或>=28周,早产儿死亡至出生后第7天)。产妇并发症发生率分别为50.4%、50.7%和25.8%。其他围产期晚期死亡的母亲是健康的。产妇高血压和产科出血更有可能发生在死产中(p=
Background: Reviews of perinatal deaths are mostly facility based. Given the number of women who, globally, deliver outside of facilities, this data may be biased against total population data. We aimed to analyse population based perinatal mortality data from a LMIC setting (Mpumalanga, South Africa) to determine the causes of perinatal death and the rate of maternal complications in the setting of a perinatal death.Methods: A secondary analysis of the South African Perinatal Problems Identification Program (PPIP) database for the Province of Mpumalanga was undertaken for the period October 2013 to January 2014, inclusive. Data on each individual late perinatal death was reviewed. We examined the frequencies of maternal and fetal or neonatal characteristics in late fetal deaths and analysed the relationships between maternal condition and fetal and/or neonatal outcomes. IBM SPSS Statistics 22.0 was used for data analysis.Results: There were 23503 births and 687 late perinatal deaths (stillbirths of >= 1000gr or >= 28 weeks gestation and early neonatal deaths up to day 7 of neonatal life) in the study period. The rate of maternal complication in macerated stillbirths, fresh stillbirths and early neonatal deaths was 50.4%, 50.7% and 25.8% respectively. Mothers in the other late perinatal deaths were healthy. Maternal hypertension and obstetric haemorrhage were more likely in stillbirths (p =