Fifteen compelling open questions in plant cell biology.
Fifteen compelling open questions in plant cell biology.
复制标题
植物细胞生物学中的15个令人信服的开放问题。
DOI：
10.1093/plcell/koab225
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发表时间：
2022-01-20
期刊：
影响因子：
--
通讯作者：
Messina C
中科院分区：
文献类型：
--
作者：
Roeder AHK;Otegui MS;Dixit R;Anderson CT;Faulkner C;Zhang Y;Harrison MJ;Kirchhelle C;Goshima G;Coate JE;Doyle JJ;Hamant O;Sugimoto K;Dolan L;Meyer H;Ehrhardt DW;Boudaoud A;Messina C
作为科学家，我们对尚未解决的问题——我们不知道的事情——至少和对新发现一样兴奋。在这里，我们邀请了15位专家来描述植物细胞生物学中最引人注目的开放性问题。这些是他们的问题：在囊泡运输和膜重塑的不断变化下，细胞器的身份、结构域和边界是如何维持的？植物皮质微管细胞骨架是机械感觉器官吗？植物细胞壁合成、组装、修饰和完整性感知的细胞途径是如何联系在一起的？胞间连丝为什么打开和关闭?从液泡到细胞核有逆行信号吗？根细胞如何容纳真菌内共生体?细胞边缘在植物形态发生中的作用是什么？如何确定细胞分裂的位置？多倍体对细胞生物学的突现效应是什么，这些“规则”是如何受到细胞类型的制约的？机械力量能在植物中触发新的细胞命运吗？单个分化的体细胞如何重编程并获得多能性？极性是如何在分离的植物细胞中重新形成的？无膜细胞器和内在无序蛋白的细胞功能谱是什么？植物是如何处理内部噪音的？从复杂的动态过程中，秩序是如何在细胞中出现并传播到器官和有机体的？我们希望你发现这些问题的讨论发人深省和鼓舞人心。我们邀请了15位专家来解决他们认为在植物细胞生物学中最引人注目的开放性问题，以下是他们的问题。
As scientists, we are at least as excited about the open questions—the things we do not know—as the discoveries. Here, we asked 15 experts to describe the most compelling open questions in plant cell biology. These are their questions: How are organelle identity, domains, and boundaries maintained under the continuous flux of vesicle trafficking and membrane remodeling? Is the plant cortical microtubule cytoskeleton a mechanosensory apparatus? How are the cellular pathways of cell wall synthesis, assembly, modification, and integrity sensing linked in plants? Why do plasmodesmata open and close? Is there retrograde signaling from vacuoles to the nucleus? How do root cells accommodate fungal endosymbionts? What is the role of cell edges in plant morphogenesis? How is the cell division site determined? What are the emergent effects of polyploidy on the biology of the cell, and how are any such “rules” conditioned by cell type? Can mechanical forces trigger new cell fates in plants? How does a single differentiated somatic cell reprogram and gain pluripotency? How does polarity develop de-novo in isolated plant cells? What is the spectrum of cellular functions for membraneless organelles and intrinsically disordered proteins? How do plants deal with internal noise? How does order emerge in cells and propagate to organs and organisms from complex dynamical processes? We hope you find the discussions of these questions thought provoking and inspiring. We asked 15 experts to address what they consider to be the most compelling open questions in plant cell biology and these are their questions.
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影响因子：
7.7
作者：
Bykov YS;Schaffer M;Dodonova SO;Albert S;Plitzko JM;Baumeister W;Engel BD;Briggs JA
通讯作者：
Briggs JA
影响因子：
18
作者：
Alamos S;Reimer A;Niyogi KK;Garcia HG
通讯作者：
Garcia HG
影响因子：
16.6
作者：
Araújo IS;Pietsch JM;Keizer EM;Greese B;Balkunde R;Fleck C;Hülskamp M
通讯作者：
Hülskamp M
DOI：
10.1073/pnas.1120429109
发表时间：
2012-01-24
影响因子：
11.1
作者：
Anderson, Charles T.;Wallace, Ian S.;Somerville, Chris R.
通讯作者：
Somerville, Chris R.
影响因子：
11.6
作者：
Belda-Palazon, Borja;Rodriguez, Lesia;Rodriguez, Pedro L.
通讯作者：
Rodriguez, Pedro L.