Japanese guidelines for mutagenicity testing

Japanese guidelines for mutagenicity testing
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日本致突变性测试指南

DOI:
10.1002/em.2850210103
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发表时间:
1993
影响因子:
2.8
通讯作者:
T. Sofuni
T. Sofuni
中科院分区:
环境科学与生态学3区
文献类型:
--
作者:
T. Sofuni

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几个日本机构需要根据监管指南进行致突变性试验。虽然每个机构的指导方针都针对特定的目的,但其背后的实验原则是相似的,农林水产省[1985年]、厚生省[1990年]、劳动省[1991年]和厚生省[1992年]都发布了一般方法建议。简要介绍了日本致突变性试验的四个主要指导原则及一些修订。此外,日本指南中的几个程序,不同于其他国家或组织进行了讨论。© 1993 Wiley利斯公司© 1993 Wiley利斯公司
Several Japanese agencies are required to perform mutagenicity tests according to regulatory guidelines. Although each agency's guidelines address a specific purpose, the experimental principles behind them are similar, and general methodological recommendations have been issued by the Ministry of Agriculture, Forestry, and Fisheries [1985]; Ministry of Health and Welfare [1990]; Ministry of Labor [1991]; and Ministry of Health and Welfare [1992]. Four major guidelines for mutagenicity testing in Japan and some amendments are briefly introduced. In addition, several procedures in Japanese guidelines that differ from those of other countries or organizations are discussed. © 1993 Wiley‐Liss, Inc. © 1993 Wiley‐Liss, Inc.