BIOCHEMICAL EFA STATUS OF MOTHERS AND THEIR NEONATES AFTER NORMAL-PREGNANCY
BIOCHEMICAL EFA STATUS OF MOTHERS AND THEIR NEONATES AFTER NORMAL-PREGNANCY
复制标题
DOI：
10.1016/0378-3782(90)90031-d
复制
发表时间：
1990-12-01
影响因子：
2.5
通讯作者：
HUISJES, HJ
中科院分区：
文献类型：
--
作者：
AL, MDM;HORNSTRA, G;HUISJES, HJ
通过测定从脐动脉和静脉组织、血细胞（BC）和血浆中分离的磷脂（PL）、从母体静脉血浆和BC中分离的磷脂（PL）、脐动脉组织的PL（传出胎儿血管）比脐静脉组织（传入胎儿血管）含有更少的（n-6）家族的脂肪酸和更多的（n-9）家族的脂肪酸。 动脉血浆中（n-6）和（n-3）脂肪酸的相对含量低于静脉血浆。 米德酸，20：3（n-9），其存在表明一个穷人的EFA状态，是5倍，在传出比传入索血管。 在新生儿血浆和BC中，它是母体水平的两倍。 在一般情况下，胎盘PL的脂肪酸组成表现出可比的模式，新生儿静脉血浆PL。这些研究结果表明，正常妊娠后的新生儿的生化EFA状态是不理想的。 新生儿和母亲EFA之间的显着相关性表明，新生儿EFA的状态取决于母亲饮食中的EFA含量。
The essential fatty acid (EFA) status of neonates was compared with that of their mothers by determining the fatty acid compositions of phospholipids (PL), isolated from umbilical arterial and venous tissue, blood cells (BC) and plasma, from maternal venous plasma and BC, and from non-infarcted placental tissue.The PL of umbilical arterial tissue (efferent fetal vessels) contained fewer fatty acids of the (n-6) family and more of the (n-9) family than umbilical venous tissue (afferent fetal vessel). The relative amounts of (n-6) and (n-3) fatty acids were less in arterial than in venous plasma. Mead acid, 20:3(n-9), the presence of which indicates a poor EFA status, was 5 times higher in the efferent than in afferent cord vessels. In neonatal plasma and BC it was twice as high as compared with maternal levels. In general, the fatty acid composition of the placenta PL showed a comparable pattern as neonatal venous plasma PL.These findings demonstrate that the biochemical EFA status of neonates after a normal pregnancy is not optimal. The significant correlations between neonatal and maternal EFAs indicate that the neonatal EFA status depends on the EFA content of the maternal diet.