Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria.
Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria.
复制标题
酵母线粒体中氧化磷酸化酶的超复杂组织。
DOI：
10.1007/s10863-008-9168-4
复制
发表时间：
2008
影响因子：
3
通讯作者：
Stuart,RosemaryA
中科院分区：
文献类型：
--
作者：
Stuart,RosemaryA
越来越多的证据表明，参与线粒体氧化磷酸化(OXPHOS)的酶在线粒体内膜内共同组装成更高有序的超复合体。本文主要对酿酒酵母的氧磷超复合体进行了综述。概述了细胞色素bc1-COX超复合体种群多样性的最新证据。此外，还将讨论二聚体/寡聚体F1Fo-ATP合成酶复合体的存在及其在建立线粒体内膜脊结构中的作用。
Accumulating evidence indicates that the enzymes involved in mitochondrial oxidative phosphorylation (OXPHOS) are co-assembled into higher-ordered supercomplexes within the mitochondrial inner membrane. This review will focus largely on the OXPHOS supercomplexes of the yeastSaccharomyces cerevisiae. The recent evidence to indicate that diversity in the populations of the cytochromebc1-COX supercomplexes exist shall be outlined. In addition, the existence of dimeric/oligomeric F1Fo-ATP synthase complexes and their proposed role in establishment of the cristae architecture of the inner mitochondrial membrane shall also be discussed.