Sex differences in gout characteristics: tailoring care for women and men.
Sex differences in gout characteristics: tailoring care for women and men.
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DOI：
10.1186/s12891-017-1465-9
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发表时间：
2017-03-14
影响因子：
2.3
通讯作者：
Greenberg JD
中科院分区：
文献类型：
--
作者：
Harrold LR;Etzel CJ;Gibofsky A;Kremer JM;Pillinger MH;Saag KG;Schlesinger N;Terkeltaub R;Cox V;Greenberg JD
描述女性和男性痛风患者之间的差异。我们分析了一个由风湿病学家治疗的痛风患者的美国国家队列。与1012例男性痛风患者相比，女性痛风患者（n = 262）年龄较大（71岁vs. 61岁，p < 0.001），合并症负担更大（高血压、糖尿病、肾脏疾病和肥胖症p < 0.001）。痛风的危险因素不同，女性更经常服用利尿剂（p < 0.001），而男性更经常饮食触发（p < 0.05）。女性和男性痛风患者的特征明显不同，这表明需要量身定制治疗建议。本文的在线版本（doi：10.1186/s12891-017-1465-9）包含补充材料，可供授权用户使用。
To characterize the differences between women and men with gout. We analyzed a US national cohort of gout patients cared for by rheumatologists. Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05). The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations. The online version of this article (doi:10.1186/s12891-017-1465-9) contains supplementary material, which is available to authorized users.