STEREOSPECIFIC ENZYMATIC-HYDROLYSIS OF PHOSPHORUS-SULFUR BONDS IN CHIRAL ORGANOPHOSPHATE TRIESTERS
STEREOSPECIFIC ENZYMATIC-HYDROLYSIS OF PHOSPHORUS-SULFUR BONDS IN CHIRAL ORGANOPHOSPHATE TRIESTERS
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DOI：
10.1016/s0960-894x(01)80516-3
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发表时间：
1994-06-23
影响因子：
2.7
通讯作者：
RAUSHEL, FM
中科院分区：
文献类型：
--
作者：
CHAE, MY;POSTULA, JF;RAUSHEL, FM
The bacterial phosphotriesterase has been shown to be capable of catalyzing the hydrolysis of a P-S bond in organophosphate triesters. The V-max values for the hydrolysis of the insecticides, acephate (O, S-dimethyl N-acetylphosphoramidothioate) and methamidophos (O, S-dimethyl phosphoramidothioate) are 140 and 6 min(-1), respectively. The (Sp)-enantiomers are hydrolyzed at a rate that is 100-fold faster than the (Rp)-enantiomers.
