Three clusters of male alcoholics

Three clusters of male alcoholics
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DOI:
10.1016/s0376-8716(97)00130-0
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发表时间:
1997-12-15
影响因子:
4.2
通讯作者:
Rybakowski, J
Rybakowski, J
中科院分区:
医学2区
文献类型:
--
作者:
Hauser, J;Rybakowski, J

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该研究包括 296 名男性酗酒者,对他们的家族史、临床因素、依赖心理病理学以及心理和神经生理学测试进行了详细研究。根据五个临床因素:依赖性发病年龄、家族酗酒史、酒精相关问题的严重程度以及精神和躯体疾病的患病率,K 均值聚类分析描绘了三类酗酒者。 1型的特点是依赖性发病较晚、家族性酗酒患病率低且病程较轻。 2型的特点是较早出现依赖、父亲有严重的家族酗酒、频繁的反社会人格、严重的酒精相关问题。 3型的特点是依赖早起、有精神疾病家族史、酒精相关问题严重、精神障碍和躯体疾病患病率高。 3 型的特征可能是与高易感性和合并症相关的酗酒。这可能会形成一种独特类型的男性酗酒者。 (C) 1997 年,爱思唯尔科学爱尔兰有限公司出版。
The study comprises 296 male alcoholics in whom detailed studies of family history, clinical factors, psychopathology of dependence as well as psychological and neurophysiological tests were made. On the basis of five clinical factors: age of onset of dependence, history of familial alcoholism: severity of alcohol-related problems and the prevalence of psychiatric and somatic diseases, K-means cluster analysis delineated three types of alcoholics. Type 1 was characterized by late onset of dependence, low prevalence of familial alcoholism and mild course. Type 2 was characterized by early onset of dependence, high familial alcoholism in fathers, frequent antisocial personality, severe intensity of alcohol-related problems. Type 3 was characterized by early onset of dependence, familial history of psychiatric diseases, severe intensity of alcohol-related problems and high prevalence of psychiatric disturbances and somatic diseases. Type 3 may be characterized as alcoholism associated with high predisposition and comorbidity. This may make a distinct type of male alcoholics. (C) 1997 Published by Elsevier Science Ireland Ltd.