Prevalence of kidney damage in Australian adults: The AusDiab Kidney Study
Prevalence of kidney damage in Australian adults: The AusDiab Kidney Study
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DOI：
10.1097/01.asn.0000070152.11927.4a
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发表时间：
2003-07-01
影响因子：
13.6
通讯作者：
Atkins, RC
中科院分区：
文献类型：
--
作者：
Chadban, SJ;Briganti, EM;Atkins, RC
ESRD的发病率正在急剧增加。当在早期阶段检测到肾损伤时，进展到终末期可能会停止或减缓。肾损害通常无症状，但表现为蛋白尿、血尿或GFR降低。与社区中肾损伤患病率相关的基于人群的研究有限，特别是在美国以外。因此。通过对11，247名年龄在25岁或以上的非住院澳大利亚人进行横断面研究，确定了澳大利亚成年人群中蛋白尿、血尿和GFR降低的患病率，这些人使用分层聚类方法随机选择。对受试者进行访谈并测试蛋白尿-点尿蛋白与肌酐的比值（异常：大于或等于0.20 mg/mg）;通过尿液显微镜检查（异常：> 10，000个红细胞/毫升）或试纸（异常：1+或更高）证实的血尿-点尿试纸（异常：1+或更高）;以及减少的GFR-Cockcroft-Gault估计的GFR（异常：
The incidence of ESRD is increasing dramatically. Progression to end-stage may be halted or slowed when kidney damage is detected at an early stage. Kidney damage is frequently asymptomatic but is indicated by the presence of proteinuria, hematuria, or reduced GFR. Population-based studies relating to the prevalence of kidney damage in the community are limited, particularly outside of the United States. Therefore. the prevalence of proteinuria, hematuria, and reduced GFR in the Australian adult population was determined using a cross-sectional study of 11,247 noninstitutionalized Australians aged 25 yr or over, randomly selected using a stratified, cluster method. Subjects were interviewed and tested for proteinuria-spot urine protein to creatinine ratio (abnormal: greater than or equal to0.20 mg/mg); hematuria-spot urine dipstick (abnormal: 1+ or greater) confirmed by urine microscopy (abnormal: >10,000 red blood cells per milliliter) or dipstick (abnormal: 1+ or greater) on midstream urine sample; and reduced GFR-Cockcroft-Gault estimated GFR (abnormal: