Synthesis and temperature response analysis of magnetic-hydrogel nanocomposites
Synthesis and temperature response analysis of magnetic-hydrogel nanocomposites
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DOI：
10.1002/jbm.a.30962
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发表时间：
2007-01-01
影响因子：
4.9
通讯作者：
Hilt, J. Zach
中科院分区：
文献类型：
--
作者：
Frimpong, Reynolds A.;Fraser, Stew;Hilt, J. Zach
开发了基于磁性纳米颗粒和温度响应水凝胶复合材料的磁响应水凝胶网络。这些系统作为微米级和纳米级设备的活性组件显示出巨大的前景，并有望在各种生物医学应用中具有广泛的适用性。具体而言，合成并表征了基于温度敏感的N-异丙基丙烯酰胺水凝胶与乙二醇二甲基丙烯酸酯、四甘醇二甲基丙烯酸酯和聚(乙二醇)400二甲基丙烯酸酯(PEG400DMA)交联的纳米复合水凝胶系统。该复合体系是通过紫外自由基聚合合成的。通过聚合纳米颗粒和单体溶液的混合物，将氧化铁磁性纳米颗粒掺入水凝胶系统中。研究了这些复合系统对不同交联分子量、温度的溶胀响应以及磁性纳米颗粒存在的影响。 (c) 2006 年 Wiley 期刊公司
Magnetically responsive hydrogel networks based on composites of magnetic nanoparticles and temperature responsive hydrogels were developed. These systems show great promise as active components of microscale and nanoscale devices and are expected to have a wide applicability in various biomedical applications. Specifically, nanocomposite hydrogel systems based on the temperature sensitive N-isopropylacrylamide hydrogels crosslinked with ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, and poly(ethylene glycol) 400 dimethacrylate (PEG400DMA) were synthesized and characterized. The composite systems were synthesized by UV free-radical polymerization. Iron oxide magnetic nanoparticles were incorporated into the hydrogel systems by polymerizing mixtures of the nanoparticles and monomer solutions. The swelling response of these composite systems to different crosslinking molecular weights, temperature, and the effect of the presence of the magnetic nanoparticles were examined. (c) 2006 Wiley Periodicals, Inc.