Human Ia-like antigens in non-lymphoid organs.

Human Ia-like antigens in non-lymphoid organs.
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非淋巴器官中的人类 Ia 样抗原。

DOI:
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发表时间:
1979
期刊:
影响因子:
6.4
通讯作者:
D. Pressman
D. Pressman
中科院分区:
医学2区
文献类型:
--
作者:
K. Koyama;T. Fukunishi;M. Barcos;N. Tanigaki;D. Pressman

文献摘要

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Human Ia-like antigens in liver and kidney were shown by the immunofluorescence assay to be present mostly in the endothelial-mesenchymal cells of these organs. The parenchymal cells apparently contained no human Ia-like antigens. The antigens in liver and kidney were purified and shown to have the same subunit structure as human Ia-like antigens of cultured B-lymphoid cells. The human Ia-like antigens in non-lymphoid organs, not only in liver and kidney but also in testis, heart, muscle and brain, carried all the xenoantigenic characteristics of human Ia-like antigens expressed on lymphoid cells of B-cell lineage.