Premature saccades: A detailed physiological analysis
Premature saccades: A detailed physiological analysis
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过早眼跳：详细的生理分析
DOI：
10.1016/j.clinph.2020.09.026
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发表时间：
2021
影响因子：
4.7
通讯作者：
Yasuo Terao
中科院分区：
文献类型：
--
作者：
Shin-Ichi Tokushige;Shunichi Matsuda;Satomi Inomata-Terada;Masashi Hamada;Yoshikazu Ugawa;Shoji Tsuji;Yasuo Terao
过早扫视（PS）是指眼跳过短，方向和幅度无法专门编程的情况。我们试图确定需要建立准确的方向和幅度的最小潜伏期，并观察发生了什么时，扫视发射之前，这个最小latency.MethodsIn实验1，249名正常受试者进行了差距扫视任务与水平的目标。实验二，28名正常被试在八个方向放置目标物，完成差距眼跳任务。在实验3中，38名正常受试者，49例帕金森病（PD），和10例脊髓小脑变性（SCD）进行了差距扫视任务与水平targets.ResultsIn实验1，它需要100毫秒，准确地建立扫视幅度和方向。然而，在实验2中，精确的幅度和方向建立所需的延迟都约为150 ms。在实验3中，PD和SCD患者的PS频率低于正常subjects.ConclusionsThe扫视幅度和方向同时确定，100-150 ms后的目标presentation。PS可能是由于对即将到来的目标方向的预测或上级丘中潜在的扫视活动引起的。
ObjectivePremature saccades (PSs) are those made with latencies too short for the direction and amplitude to be specifically programmed. We sought to determine the minimum latency needed to establish accurate direction and amplitude, and observed what occurs when saccades are launched before this minimum latency.MethodsIn Experiment 1, 249 normal subjects performed the gap saccade task with horizontal targets. In Experiment 2, 28 normal subjects performed the gap saccade task with the targets placed in eight directions. In Experiment 3, 38 normal subjects, 49 patients with Parkinson’s disease (PD), and 10 patients with spinocerebellar degeneration (SCD) performed the gap saccade task with horizontal targets.ResultsIn Experiment 1, it took 100 ms to accurately establish saccade amplitudes and directions. In Experiment 2, however, the latencies needed for accurate amplitude and direction establishment were both approximately 150 ms. In Experiment 3, the frequencies of PSs in patients with PD and SCD were lower than those of normal subjects.ConclusionsThe saccade amplitudes and directions are determined simultaneously, 100–150 ms after target presentation. PSs may result from prediction of the oncoming target direction or latent saccade activities in the superior colliculus.SignificanceSaccade direction and amplitude are determined simultaneously.