Response to Brosch et al.

Response to Brosch et al.
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DOI:
10.1016/j.cmet.2012.02.005
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发表时间:
2012-03-07
期刊:
影响因子:
29
通讯作者:
Patti ME
Patti ME
中科院分区:
生物学1区
文献类型:
--
作者:
Pihlajamäki J;Lerin C;Kaminska D;Venesmaa S;Itkonen P;Boes T;Floss T;Schroeder J;Dearie F;Crunkhorn S;Burak F;Jimenez-Chillaron JC;Kuulasmaa T;Miettinen P;Park PJ;Nasser I;Zhao Z;Zhang Z;Xu Y;Wurst W;Ren H;Morris AJ;Stamm S;Goldfine AB;Laakso M;Patti ME

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We would like to respond to Brosch et al. regarding our manuscript “Expression of the Splicing Factor Gene SFRS10 Is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis”. Brosch performed RT-PCR in liver samples from 13 lean and 34 obese individuals, finding no differences in SFRS10 or LPIN1 expression. We wish to address points raised by Brosch, including experimental strategy and analysis of human SFRS10 expression.
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