Alasmontamine A, A First Tetrakis Monoterpene Indole Alkaloid from Tabernaemontana elegans
Alasmontamine A, A First Tetrakis Monoterpene Indole Alkaloid from Tabernaemontana elegans
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DOI：
10.1021/ol902420s
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发表时间：
2009-12-17
期刊：
影响因子：
5.2
通讯作者：
Morita, Hiroshi
中科院分区：
文献类型：
--
作者：
Hirasawa, Yusuke;Miyama, Saori;Morita, Hiroshi
从秀丽竹叶中分离得到一种新的四单萜吲哚生物碱--谷氨酰胺A(1)，它由双Vobtusine骨架组成。根据光谱数据，确定了该化合物的结构，包括相对的立体化学。AlasmontamineA(1)对HL-60细胞具有中等的生长抑制活性。
A novel tetrakis monoterpene indole alkaloid, alasmontamine A (1) consisting of bis-vobtusine-type skeletons, was isolated from the leaves of Tabernaemontana elegans. The structure including the relative stereochemistry was elucidated on the basis of spectroscopic data. Alasmontamine A (1) exhibited moderate cell growth inhibitory activity against HL-60 cells.