Role of the Deep Eutectic Solvent Reline in the Synthesis of Gold Nanoparticles.
Role of the Deep Eutectic Solvent Reline in the Synthesis of Gold Nanoparticles.
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DOI：
10.1021/acssuschemeng.2c07337
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发表时间：
2023-07-17
影响因子：
8.4
通讯作者：
Torrente-Murciano L
中科院分区：
文献类型：
--
作者：
Datta S;Mahin J;Liberti E;Manasi I;Edler KJ;Torrente-Murciano L
这项工作提出了一个小的（<3 nm）的金纳米粒子在无毒，环保，可生物降解的氯化胆碱和尿素（reline）的低共熔混合物的合成机制的理解，而无需添加外部还原剂或稳定剂。Reline通过释放氨（通过尿素水解）充当还原剂，即使在微量氨浓度水平下也能形成金纳米颗粒。Reline还影响金前体的形态形成金氯络合物，稳定Au+物质，导致更容易还原并避免否则快速的还原反应。然而，这种能力在大量水的存在下丧失，其中水取代了前体形态中的氯化物配体。此外，RELINE作为弱稳定剂，导致小颗粒（<3 nm）和窄分布，尽管团聚体迅速形成。这种性质在水的存在下保持，表明它与尿素稳定而不是氢键网络有关。这项工作具有重要的意义，在绿色合成领域的纳米粒子的小尺寸，特别是生物医学和医疗保健应用，由于无毒的性质，与传统的路线相比，低共熔溶剂的成分。无毒、环保和可生物降解的低共熔混合物可以取代金属纳米颗粒合成中的外部还原剂和稳定剂。
This work presents a mechanistic understanding of the synthesis of small (<3 nm) gold nanoparticles in a nontoxic, eco-friendly, and biodegradable eutectic mixture of choline chloride and urea (reline) without the addition of external reducing or stabilization agents. Reline acts as a reducing agent by releasing ammonia (via urea hydrolysis), forming gold nanoparticles even at trace ammonia concentration levels. Reline also affects the speciation of the gold precursor forming gold chloro-complexes, stabilizing Au+ species, leading to an easier reduction and avoiding the otherwise fast disproportionation reaction. Such a capability is however lost in the presence of large amounts of water, where water replaces the chloride ligands in the precursor speciation. In addition, reline acts as a weak stabilizing agent, leading to small particles (<3 nm) and narrow distributions although agglomerates quickly form. Such properties are maintained in the presence of water, indicating that it is linked to the urea stabilization rather than the hydrogen-bonding network. This work has important implications in the field of green synthesis of nanoparticles with small sizes, especially for biomedical and health care applications, due to the nontoxic nature of the components of deep eutectic solvents in contrast to the conventional routes. Nontoxic, eco-friendly, and biodegradable eutectic mixtures can replace external reducing and stabilization agents in the synthesis of metal nanoparticles.
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影响因子：
16.6
作者：
Hammond OS;Edler KJ;Bowron DT;Torrente-Murciano L
通讯作者：
Torrente-Murciano L
影响因子：
9.8
作者：
Haerens, Kurt;Matthijs, Edward;Van der Bruggen, Bart
通讯作者：
Van der Bruggen, Bart
影响因子：
4.1
作者：
Kumari, Pratibha;Shobhna;Kashyap, Hemant K.
通讯作者：
Kashyap, Hemant K.
影响因子：
3.9
作者：
Chirea, Mariana;Freitas, Andreia;Silva, Fernando
通讯作者：
Silva, Fernando
影响因子：
4.6
作者：
De Vreese, Peter;Brooks, Neil R.;Van Deun, Rik
通讯作者：
Van Deun, Rik