Primary versus secondary ovarian malignancy: Imaging findings of adnexal masses in the Radiology Diagnostic Oncology Group Study
Primary versus secondary ovarian malignancy: Imaging findings of adnexal masses in the Radiology Diagnostic Oncology Group Study
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DOI：
10.1148/radiology.219.1.r01ap28213
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发表时间：
2001-04-01
期刊：
影响因子：
19.7
通讯作者：
Kurtz, AB
中科院分区：
文献类型：
--
作者：
Brown, DL;Zou, KH;Kurtz, AB
目的：分析卵巢原发和继发恶性肿瘤的超声(US)、计算机体层摄影(CT)和磁共振(MR)影像特征，以确定两者的表现是否有显著差异。材料和方法：分析多机构放射诊断肿瘤组的资料，包括86例原发卵巢癌和24例继发性卵巢肿瘤。结果：在所有三种成像方法评估的影像特征中，US(P=0.02)或MR(P=0.01)所确定的多房性是唯一显著的特征。在美国，81例原发卵巢癌中有30例(37%)是多房的，而24例转移性肿瘤中只有3例(12%)是多房的。在磁共振成像中，54例原发卵巢癌中有40例(74%)是多房的，而14例转移性肿瘤中只有5例(36%)是多房的。结论：对于卵巢恶性肿块，MRI或US的多房性表现更有利于卵巢原发恶性肿瘤的诊断，但难以准确区分卵巢原发和继发肿瘤。
PURPOSE: To analyze ultrasonographic (US), computed tomographic (CT), and magnetic resonance (MR) imaging features of primary and secondary ovarian malignant neoplasms to determine if there is any significant difference in their appearance.MATERIALS AND METHODS: Analysis of the multi-institutional Radiology Diagnostic Oncology Group data revealed 86 patients with primary ovarian carcinoma and 24 patients with a secondary ovarian neoplasm. Numerous imaging features that had been recorded for the adnexal masses with each imaging modality were reviewed and compared between primary and secondary malignant ovarian neoplasms.RESULTS: Of the imaging features assessed with all three modalities, multilocularity as determined at US (P =.02) or MR imaging (P =.01) was the only significant feature. At US, 30 (37%) of 81 primary ovarian cancers were multilocular, whereas only three (12%) of 24 metastatic neoplasms were multilocular. At MR imaging, 40 (74%) of 54 primary ovarian cancers were multilocular, whereas only five (36%)of 14 metastatic neoplasms were multilocular. Neither a predominately solid appearance nor bilaterality was significantly different between primary and secondary neoplasms.CONCLUSION: For malignant ovarian masses, multilocularity at MR imaging or US favors the diagnosis of primary ovarian malignancy rather than secondary neoplasm, but it is difficult to accurately distinguish between primary and secondary ovarian malignancies.