Vitrectomy does not increase the risk of open-angle glaucoma or ocular hypertension-a 5-year follow-up
Vitrectomy does not increase the risk of open-angle glaucoma or ocular hypertension-a 5-year follow-up
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DOI：
10.1007/s00417-010-1409-7
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发表时间：
2010-10-01
影响因子：
2.7
通讯作者：
Welge-Lussen, Ulrich
中科院分区：
文献类型：
--
作者：
Yu, Alice L.;Brummeisl, Wolfgang;Welge-Lussen, Ulrich
本研究旨在探讨有晶状体眼和人工晶状体眼玻璃体切除术后迟发性开角型青光眼(OAG)或高眼压的发生情况。比较玻璃体切除组和对照眼的OAG和高眼压的发生情况。此外，还分析了晶状体状态(有晶状体或人工晶状体)对玻璃体切除眼和对照眼发生OAG或高眼压的影响。此外，还计算了双眼的平均眼压(IOP)和平均抗青光眼药物的次数。平均随访时间为79.5+/-25.6个月。玻璃体切除术后OAG 19眼(4.31%)，术后高眼压19眼(4.31%)。发生OAG 11只眼(2.49%)，高眼压13只眼(2.95%)。玻璃体切除组和对照眼在发生OAG或高眼压方面没有统计学意义上的差异。此外，玻璃体切除眼的晶状体状态不影响OAG的晚期发展或高眼压。两眼的平均眼压和平均抗青光眼药物数没有显著差异。与以往的报道相比，我们没有观察到玻璃体手术后迟发性OAG或高眼压的发生率增加。同样，摘除晶状体不会增加玻璃体切除眼OAG或高眼压的风险。
The goal of this study was to investigate the development of late onset open-angle glaucoma (OAG) or ocular hypertension after vitrectomy in phakic and pseudophakic eyes.In this retrospective case series, the records of 441 patients who had undergone vitrectomy in one eye by a single surgeon were reviewed. The development of OAG or ocular hypertension in the vitrectomized and fellow control eyes was compared. Furthermore, the influence of the lens status (phakic or pseudophakic) on the onset of OAG or ocular hypertension in the vitrectomized and fellow control eyes was analysed. Additionally, the mean intraocular pressure (IOP) and the mean number of antiglaucomatous medications were calculated for both eyes.A mean follow-up period of 79.5 +/- 25.6 months was achieved. There were 19 vitrectomized eyes (4.31%) with postoperative OAG, and 19 vitrectomized eyes (4.31%) with postoperative ocular hypertension. Eleven control eyes (2.49%) had OAG, and 13 control eyes (2.95%) ocular hypertension. There were no statistically significant differences in the development of OAG or ocular hypertension between the vitrectomized and fellow control eyes. Furthermore, the lens status in vitrectomized eyes did not influence the late development of OAG or ocular hypertension. There were no significant differences in the mean IOP and the mean number of antiglaucomatous medications between the two eyes.Contrary to previous reports, we could not observe an increased incidence of late onset OAG or ocular hypertension after vitrectomy. Similarly, the removal of the lens did not increase the risk of OAG or ocular hypertension in vitrectomized eyes.