Fc and C3b receptors on pulmonary endothelial cells: induction by injury.
Fc and C3b receptors on pulmonary endothelial cells: induction by injury.
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肺内皮细胞上的 Fc 和 C3b 受体：损伤诱导。
DOI：
10.1126/science.6270789
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Ruan,JW
中科院分区：
文献类型：
--
作者：
Ryan,US;Schultz,DR;Ruan,JW
活化的补体第三组分和免疫球蛋白G的Fc部分的受体不被明显正常的牛肺内皮细胞表达，但当细胞暴露于白色细胞裂解物或感染流感病毒或巨细胞病毒时表达。这些潜在受体的暴露可能导致肺部炎症反应，例如过敏反应和那些以免疫复合物沉积为特征的肺部疾病。
Receptors for the activated third component of complement and for the Fc portion of immunoglobulin G are not expressed by apparently normal bovine pulmonary endothelial cells, but are expressed when the cells are exposed to white cell lysates or are infected with influenza or cytomegalovirus. The unmasking of these latent receptors may contribute to the pulmonary inflammatory response characteristic of, for example, anaphylaxis and to those lung diseases characterized by the deposition of immune complexes.