Granules of cytolytic T‐lymphocytes contain two serine esterases.
Granules of cytolytic T‐lymphocytes contain two serine esterases.
复制标题
溶细胞性 T 淋巴细胞颗粒含有两种丝氨酸酯酶。
作者：
Daniele Masson;Markus Nabholzl;Christine Estrade;Jurg Tschopp
来自细胞溶解性T淋巴细胞（CTL）的细胞质颗粒含有两种蛋白质，它们与丝氨酸酯酶特异性亲和标记二异丙基氟磷酸（DFP）反应。其中之一是胰蛋白酶样酯酶，它由两个二硫连接的35 - kd亚基组成。另一个由一条29 - kd链组成。在CTL衍生的T细胞杂交中，这两种分子与细胞溶解活性和穿孔素活性同时被诱导。
Cytoplasmic granules from cytolytic T‐lymphocytes (CTL) contain two proteins which react with the serine esterase‐specific affinity label diisopropylfluorophosphate (DFP). One of these is a trypsin‐like esterase which consists of two disulfide‐linked 35‐kd subunits. The other consists of a single 29‐kd chain. Both molecules are induced concomitantly with cytolytic activity and perforin activity in a CTL‐derived T‐cell hybrid.