BLAST 2 SEQUENCES, a new tool for comparing protein and nucleotide sequences
BLAST 2 SEQUENCES, a new tool for comparing protein and nucleotide sequences
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DOI：
10.1016/s0378-1097(99)00149-4
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发表时间：
1999-05-15
影响因子：
2.1
通讯作者：
Madden, TL
中科院分区：
文献类型：
--
作者：
Tatusova, TA;Madden, TL
介绍了一种新的基于BLAST的蛋白质或核苷酸序列比对工具“BLAST 2 SEQUENCES”。虽然标准BLAST程序被广泛用于在核苷酸和蛋白质数据库中搜索同源序列，但通常只需要比较两个已知同源的序列，它们来自相关物种或例如相同病毒的不同分离株。在这种情况下，搜索整个数据库将是不必要的耗时。“BLAST 2 SEQUENCES”利用BLAST算法进行成对DNA-DNA或蛋白质-蛋白质序列比较。该程序的万维网版本可在NCBI万维网网址（http：//www.ncbi.nlm.nih.gov/gorf/bl2.html）上交互使用。所得到的比对结果以图形和文本形式呈现。可从NCBI FTP站点（ftp：//www.example.com）下载用于PC（Windows）、Mac和若干基于UNIX的平台的程序变体。ncbi.nlm.nih.gov (C)1999年由Elsevier Science B. V.出版，版权所有。
'BLAST 2 SEQUENCES', a new BLAST-based tool for aligning two protein or nucleotide sequences, is described. While the standard BLAST program is widely used to search for homologous sequences in nucleotide and protein databases, one often needs to compare only two sequences that are already known to be homologous, coming from related species or, e.g. different isolates of the same virus. In such cases searching the entire database would be unnecessarily time-consuming. 'BLAST 2 SEQUENCES' utilizes the BLAST algorithm for pairwise DNA-DNA or protein-protein sequence comparison. A World Wide Web version of the program can be used interactively at the NCBI WWW site (http://www.ncbi.nlm.nih.gov/gorf/bl2.html). The resulting alignments are presented in both graphical and text form. The variants of the program for PC (Windows), Mac and several UNIX-based platforms can be downloaded from the NCBI FTP site (ftp://ncbi.nlm.nih.gov). (C) 1999 Published by Elsevier Science B.V. All rights reserved.