Brain-to-body ratios and time of maturation of the mouse brain.
Brain-to-body ratios and time of maturation of the mouse brain.
复制标题
小鼠大脑的大脑与身体的比率和成熟时间。
DOI：
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发表时间：
1963
影响因子：
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通讯作者：
Tsukasa Kobayashi
中科院分区：
文献类型：
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作者：
Tsukasa Kobayashi
对 218 只小鼠进行了发育过程中脑重量与体重关系的研究，结果揭示了三个不同的阶段。在第一阶段，比率相对恒定。持续时间短的第二阶段的特点是突然减少。在最持久的第三阶段，比率再次呈现更恒定的值。比率的突然变化发生在 14 天龄左右。一般认为，该比率的突然变化是大脑成熟的指标，因为在第 15 天左右还有其他几个参数接近成熟水平。对其他物种数据的审查支持了这一建议。
Studies on the relationships of brain weight to body weight during development were conducted in 218 mice, and revealed three distinct phases. During the first phase, the ratios are relatively constant. The second phase of short duration is characterized by abrupt reductions. In the third phase, which is the most enduring, the ratios again assume more constant values. The abrupt change in the ratios took place around 14 days of age. It is suggested that the abrupt change in the ratio is, in general, an indicator of the maturation of the brain, because there are several other parameters which approach mature levels around the 15th day. A review of the data on other species supports this suggestion.