HOW COMMON IS CATAMENIAL EPILEPSY

HOW COMMON IS CATAMENIAL EPILEPSY
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DOI:
10.1111/j.1528-1157.1993.tb02097.x
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发表时间:
1993-09-01
期刊:
影响因子:
5.6
通讯作者:
BRODIE, MJ
BRODIE, MJ
中科院分区:
医学1区
文献类型:
--
作者:
DUNCAN, S;READ, CL;BRODIE, MJ

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对40例难治性癫痫育龄妇女进行连续3个月的癫痫发作、月经初潮、月经末期及经前紧张症状的记录。将月经性癫痫定义为每月至少75%的癫痫发作发生在10天的时间范围内,包括月经前4天和发病后6天,只有5名妇女(12.5%)符合标准。然而,在研究完成后,这些患者中的31人(78%)声称他们的大部分癫痫发作发生在月经前后,并因月经而加重。月经性癫痫患者报告的经前紧张症状并不比这组中的其他人多。在另外4名患者中发现了月经周期外的集聚现象。月经性癫痫是一种罕见的疾病。患者声称与月经有关的癫痫发作频率并不总是准确的。应采用标准定义,因为该诊断对管理有影响。
Forty women of childbearing age with refractory epilepsy were asked to record their seizures, the first and last days of their menstrual periods, and symptoms of premenstrual tension for 3 consecutive months. By defining catamenial epilepsy as the occurrence of at least 75% of seizures each month in the 10-day time frame, which included the 4 days preceding menstruation and the 6 days after its onset, only 5 women (12.5%) were identified who fulfilled the criterion. Nevertheless, after the study was completed, 31 (78%) of these patients claimed that most of their seizures occurred near the time of and were exacerbated by menstruation. The patients with catamenial epilepsy reported no more symptoms of premenstrual tension than did the rest of the group. Clustering outside the menstrual cycle was noted in 4 other patients. Catamenial epilepsy is an uncommon condition. Patient claims about frequency of seizures in relation to menstruation are not always accurate. A standard definition should be adopted because the diagnosis has implications for management.